Dosage compensation is the regulation of X-Chromosome expression to ensure equal phenotype expression in both males and females of a species. Equal expression is typically achieved by silencing one of the X Chromosomes in females.

However, biological methods for dosage compensation can be regulated differently depending on the species. For example, male fruit flies double the expression of genes along the X chromosome instead of full inactivation of one of the female X chromosomes.

Wikipedia & Dosage compensation in Drosophila, Stanford University.

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